Well I guess it depends on what you do. The papers I put together for submission to journals are written in Word. I'm a microscopist, so the images are exported from the imaging software and cropped and processed using Adobe Photoshop. For graphs and spectra I export raw data into Microcal Origin.

LaTeX works well too, but I have no interest in learning the scripting format, so until a really good WYSIWYG editor comes out (and I have yet to see a "good" one designed for non-coder guys like me) then I'm sticking to Word.